Three Strands Bio
In development · California, USA.

Children's teeth come in on a schedule. So should their oral care.

Three Strands Bio is building prebiotic oral care for kids

The problem

Tooth decay is still the most common chronic disease of childhood.

It isn't caused by bacteria in general — it's caused by an ecosystem tipping out of balance, usually early, and usually for years before a cavity is visible. Most children's toothpaste is built to scrub and to kill broadly. Very little of it is designed around what is actually living in a two-year-old's mouth, or how that changes by the time she's six.

What makes it different

Prebiotic first. Named strains, not vague ones.

Feed, don't scorch
Substrates and pH conditions chosen to favor the resident species associated with a stable mouth, instead of a broad antibacterial approach that clears everything.
Built chairside
Co-founded with a practicing San Francisco dentist, so the formulation has to survive real pediatric appointments — not just a lab bench.
First product
In formulation — not yet for sale

Prebiotic toothpaste for children

Our first release. Sample packs for dental offices will go out before general availability — if you run a practice and want to be on that list, get in touch.

Age range
0 to 5 years olds
Fluoride
Under evaluation; both fluoride and fluoride-free versions are being assessed
Expected
TBA

© 2026 Three Strands Bio, Inc. · Burlingame, California

Products described on this page are in development and are not available for purchase. Nothing here is a medical claim or a substitute for advice from your child's dentist or pediatrician.